Spicule Retinol PDRN Cream

An anti-ageing shot in a 15g tube, featuring 2,000ppm marine spicules that engineer the delivery channels, nano-liposomal retinol fills them in with serious cell-renewal actives, and CICA PDRN repairs what it finds. 

This cream is an anti-ageing powerhouse. Apply it at night and within a minute or two, you will feel a gentle, buzzing tingle on the skin - that's the 200,000 or so micro-spicules per tube (1/40th the size of a pore) creating temporary micro-channels in the skin's surface, building a delivery system. And what gets delivered through those channels is where this formula shines: nano-liposomal retinol at 1,000ppm, encapsulated in tiny lipid spheres that protect it from degrading before it reaches the skin and release it gradually for reduced irritation and better results. Clinically, this formula has been evaluated for triple improvement in pore depth, area, and density, as well as improvements in fine lines around the eyes and smile lines, overall skin texture, and firmness.

The PDRN here is a Cica-derived Sodium DNA, which brings centella's calming and regenerative properties to the cellular repair work alongside the DNA-based ingredient itself. It's a smart pairing with retinol: where retinol accelerates cell turnover and can temporarily sensitise skin in the process, PDRN actively supports tissue repair and barrier restoration, softening the adjustment period and making this genuinely usable for skin types that have previously found retinol too much. Surrounding all three power actives is what Mary & May calls the Safe 4X Formula: 2% panthenol, ceramide NP, hyaluronic acid, and allantoin working together to keep the skin calm, hydrated, and intact while the actives do their thing.

Night use only. Expect the tingle - it settles.

15g

Who its for: All skin types that need to address signs of ageing such as enlarged pores, roguh texture, and loss of elasticity

What it does: An intensive nightly anti-ageing treatment for anyone who wants retinol results without the retinol irritation; spicules open the path, nano-liposomal retinol gets to work, and CDRN + a full barrier complex keep skin calm through all of it.

Apply in either the serum or moisturiser step of your skincare routine, depending on your hydration needs. Start 2 to 3 nights per week and build to nightly use as skin adjusts. Always follow with SPF the next morning. Do not use on the same night as other exfoliating actives.

Aqua(Water), Methylpropanediol, Glycerin, 1,2-Hexanediol, Niacinamide, Panthenol, Caprylic/Capric Triglyceride, Polypropylsilsesquioxane, C14-22 Alcohols, Ammonium Acryloyldimethyltaurate/VP Copolymer, Glyceryl Stearate, Cetyl Ethylhexanoate, Vinyl Dimethicone, Macadamia Ternifolia Seed Oil, Brassica Campestris (Rapeseed) Sterols, Polyglyceryl-10 Laurate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, C12- 20 Alkyl Glucoside, Arginine, Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate, Cholesterol, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydrolyzed Sponge, Polyisobutene, Gardenia Florida Fruit Extract, Tocopherol, Allantoin, Ethylhexylglycerin, Butyrospermum Parkii (Shea) Butter, Retinol, Xanthan Gum, Hydrogenated Lecithin, Sodium Hyaluronate, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Adenosine, Dextrin, Helianthus Annuus (Sunflower) Seed Oil, Lauryl Glucoside, Polyglutamic Acid, Polyglyceryl-6 Laurate, Disodium EDTA, Ceramide NP, Caprylyl/Capryl Glucoside, Sorbitan Oleate, Myristyl Glucoside, Stearic Acid, Benzotriazolyl Dodecyl p-Cresol, Glyceryl Acrylate/Acrylic Acid Copolymer, Oleic Acid, PVM/MA Copolymer, Beta-Carotene, Sodium DNA